IRS-1 (phospho Ser1101) rabbit pAb

• Background :

  This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009]

• Description :

  This gene encodes a protein which is phosphorylated by insulin receptor tyrosine kinase. Mutations in this gene are associated with type II diabetes and susceptibility to insulin resistance. [provided by RefSeq, Nov 2009],

• Product Name Alternative :

  IRS1; Insulin receptor substrate 1; IRS-1

• UniProt :

  P35568

• Swiss Prot :

  P35568

• Reactivity :

  Human; Mouse; Rat; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human IRS-1 around the phosphorylation site of Ser1101. AA range:1067-1116

• Target :

  IRS-1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  170kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  170kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus, cytoplasm, cytosol, plasma membrane, insulin receptor complex, caveola, intracellular membrane-bounded organelle

• Other Product Names :

  IRS1; Insulin receptor substrate 1; IRS-1

• Gene ID (Human) :

  3667