Integrin β3 (phospho Tyr785) rabbit pAb

• Background :

  The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008]

• Description :

  The ITGB3 protein product is the integrin beta chain beta 3. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. Integrin beta 3 is found along with the alpha IIb chain in platelets. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. [provided by RefSeq, Jul 2008],

• UniProt :

  P05106

• Swiss Prot :

  P05106

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human Integrin beta3 around the phosphorylation site of Tyr785. AA range:739-788

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  IF/ICC 1:50-300; ELISA 1:2000-20000; IHC-p 1:50-200

• Molecular Weight :

  87kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  87kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Single-pass type I membrane protein . Cell projection, lamellipodium membrane . Cell junction, focal adhesion . Cell junction, synapse, postsynaptic cell membrane ; Single-pass type I membrane protein . Cell junction, synapse .

• Other Product Names :

  ITGB3; GP3A; Integrin beta-3; Platelet membrane glycoprotein IIIa; GPIIIa; CD antigen CD61

• Gene ID (Human) :

  3690