AIFL rabbit pAb

• Background :

  Domain:The Rieske domain induces apoptosis., function:Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential., similarity:Belongs to the FAD-dependent oxidoreductase family., similarity:Contains 1 Rieske domain., subcellular location:Does not translocate to the nucleus upon induction of apoptosis., tissue specificity:Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level) .

• Description :

  Domain: The Rieske domain induces apoptosis. function: Induces apoptosis through a caspase dependent pathway. Reduces mitochondrial membrane potential. similarity: Belongs to the FAD-dependent oxidoreductase family. similarity: Contains 1 Rieske domain. subcellular location: Does not translocate to the nucleus upon induction of apoptosis. tissue specificity: Ubiquitous. Expressed in bone marrow, cerebral cortex, liver, ovary, thymus, thyroid gland and tongue (at protein level).

• Product Name Alternative :

  AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

• UniProt :

  Q96NN9

• Swiss Prot :

  Q96NN9

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human AIFM3. AA range:10-59

• Target :

  AIFL

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  67kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  67kD

• Fragment :

  IgG

• Subcellular Location :

  Mitochondrion . Does not translocate to the nucleus upon induction of apoptosis.

• Other Product Names :

  AIFM3; AIFL; Apoptosis-inducing factor 3; Apoptosis-inducing factor-like protein

• Gene ID (Human) :

  150209