CDC46 rabbit pAb

• Background :

  The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene is structurally very similar to the CDC46 protein from S. cerevisiae, a protein involved in the initiation of DNA replication. The encoded protein is a member of the MCM family of chromatin-binding proteins and can interact with at least two other members of this family. The encoded protein is upregulated in the transition from the G0 to G1/S phase of the cell cycle and may actively participate in cell cycle regulation. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46

• UniProt :

  P33992

• Swiss Prot :

  P33992

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MCM5. AA range:21-70

• Target :

  CDC46

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  90kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  90kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Chromosome . Cytoplasm, cytosol . Associated with chromatin before the formation of nuclei and detaches from it as DNA replication progresses. .

• Other Product Names :

  MCM5; CDC46; DNA replication licensing factor MCM5; CDC46 homolog; P1-CDC46

• Gene ID (Human) :

  4174