ChemR23 rabbit pAb

• Background :

  Developmental stage:Expressed during bone development., function:Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2) ., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.

• Description :

  Developmental stage: Expressed during bone development. function: Orphan receptor. Could be a chemotactic peptide receptor. May have a function in bone metabolism. Acts as a coreceptor for several SIV strains (SIVMAC316, SIVMAC239, SIVMACL7E-FR and SIVSM62A), as well as a primary HIV-1 strain (92UG024-2). similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Prominently expressed in developing osseous and cartilaginous tissue. Also found in adult parathyroid glands.

• UniProt :

  Q99788

• Swiss Prot :

  Q99788

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human CMKLR1. AA range:221-270

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

• Molecular Weight :

  42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  42kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Multi-pass membrane protein . Internalizes efficiently in response to RARRES2. .

• Other Product Names :

  CMKLR1; CHEMR23; DEZ; Chemokine-like receptor 1; G-protein coupled receptor ChemR23; G-protein coupled receptor DEZ

• Gene ID (Human) :

  1240