CLC-KA rabbit pAb

• Background :

  This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1

• UniProt :

  P51800

• Swiss Prot :

  P51800

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human CLCNKA. AA range:581-630

• Target :

  CLC-KA

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  75kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  75kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane; Multi-pass membrane protein.

• Other Product Names :

  CLCNKA; Chloride channel protein ClC-Ka; Chloride channel Ka; ClC-K1

• Gene ID (Human) :

  1187