Fatty Acid Synthase rabbit pAb

• Background :

  The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008]

• Description :

  The enzyme encoded by this gene is a multifunctional protein. Its main function is to catalyze the synthesis of palmitate from acetyl-CoA and malonyl-CoA, in the presence of NADPH, into long-chain saturated fatty acids. In some cancer cell lines, this protein has been found to be fused with estrogen receptor-alpha (ER-alpha), in which the N-terminus of FAS is fused in-frame with the C-terminus of ER-alpha. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  FASN; FAS; Fatty acid synthase

• UniProt :

  P49327

• Swiss Prot :

  P49327

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human Fatty Acid Synthase. AA range:1478-1527

• Target :

  Fatty Acid Synthase

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  IHC-p: 100-300.Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  273kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  273kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Melanosome . Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

• Other Product Names :

  FASN; FAS; Fatty acid synthase

• Gene ID (Human) :

  2194