GAP1-InsP4 BP rabbit pAb

• Background :

  This gene encodes a protein that binds inositol 1,3,4,5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]

• Description :

  This gene encodes a protein that binds inositol 1, 3, 4, 5-tetrakisphosphate and stimulates the GTPase activity of Ras p21. This protein functions as a negative regulator of the Ras signalling pathway. It is localized to the cell membrane via a pleckstrin homology (PH) domain in the C-terminal region. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016],

• Product Name Alternative :

  RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein

• UniProt :

  Q14644

• Swiss Prot :

  Q14644

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RASA3. AA range:247-296

• Target :

  GAP1-InsP4 BP

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  95kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  95kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane.

• Other Product Names :

  RASA3; Ras GTPase-activating protein 3; GAP1 (IP4BP) ; Ins P4-binding protein

• Gene ID (Human) :

  22821