LOK rabbit pAb

• Background :

  This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a member of the Ste20 family of serine/threonine protein kinases, and is similar to several known polo-like kinase kinases. The protein can associate with and phosphorylate polo-like kinase 1, and overexpression of a kinase-dead version of the protein interferes with normal cell cycle progression. The kinase can also negatively regulate interleukin 2 expression in T-cells via the mitogen activated protein kinase kinase 1 pathway. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase

• UniProt :

  O94804

• Swiss Prot :

  O94804

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human STK10. AA range:491-540

• Target :

  LOK

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  120kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  120kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Peripheral membrane protein .

• Other Product Names :

  STK10; LOK; Serine/threonine-protein kinase 10; Lymphocyte-oriented kinase

• Gene ID (Human) :

  6793