LRAT rabbit pAb

• Background :

  Lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT) Homo sapiens The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014]

• Description :

  Lecithin retinol acyltransferase (phosphatidylcholine--retinol O-acyltransferase) (LRAT) Homo sapiens The protein encoded by this gene localizes to the endoplasmic reticulum, where it catalyzes the esterification of all-trans-retinol into all-trans-retinyl ester. This reaction is an important step in vitamin A metabolism in the visual system. Mutations in this gene have been associated with early-onset severe retinal dystrophy and Leber congenital amaurosis 14. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2014],

• Product Name Alternative :

  LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase

• UniProt :

  O95237

• Swiss Prot :

  O95237

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human LRAT. AA range:111-160

• Target :

  LRAT

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  27kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  27kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum membrane ; Single-pass membrane protein . Rough endoplasmic reticulum . Endosome, multivesicular body . Cytoplasm, perinuclear region . Present in the rough endoplasmic reticulum and multivesicular body in hepatic stellate cells. Present in the rough endoplasmic reticulum and perinuclear region in endothelial cells (By similarity) . .

• Other Product Names :

  LRAT; Lecithin retinol acyltransferase; Phosphatidylcholine--retinol O-acyltransferase

• Gene ID (Human) :

  9227