MTHFR rabbit pAb

• Background :

  The protein encoded by this gene catalyzes the conversion of 5,10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency.[provided by RefSeq, Oct 2009]

• Description :

  The protein encoded by this gene catalyzes the conversion of 5, 10-methylenetetrahydrofolate to 5-methyltetrahydrofolate, a co-substrate for homocysteine remethylation to methionine. Genetic variation in this gene influences susceptibility to occlusive vascular disease, neural tube defects, colon cancer and acute leukemia, and mutations in this gene are associated with methylenetetrahydrofolate reductase deficiency. [provided by RefSeq, Oct 2009],

• Product Name Alternative :

  MTHFR; Methylenetetrahydrofolate reductase

• UniProt :

  P42898

• Swiss Prot :

  P42898

• Reactivity :

  Human; Mouse; Monkey

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MTHFR. AA range:314-363

• Target :

  MTHFR

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300; ELISA 2000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  75kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  75kD

• Fragment :

  IgG

• Subcellular Location :

  Cytosol, synapse

• Other Product Names :

  MTHFR; Methylenetetrahydrofolate reductase

• Gene ID (Human) :

  4524