PBFE rabbit pAb

• Background :

  Catalytic activity: (3S) -3-hydroxyacyl-CoA = trans-2 (or 3) -enoyl-CoA + H (2) O., catalytic activity: (3Z) -dodec-3-enoyl-CoA = (2E) -dodec-2-enoyl-CoA., catalytic activity: (S) -3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH., disease:Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease., pathway:Lipid metabolism; fatty acid beta-oxidation., similarity:In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family., similarity:In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family., subunit:Monomer., tissue specificity:Liver and kidney. Lower amounts seen in the brain.

• Description :

  Catalytic activity: (3S)-3-hydroxyacyl-CoA = trans-2 (or 3)-enoyl-CoA + H (2)O. Catalytic activity: (3Z)-dodec-3-enoyl-CoA = (2E)-dodec-2-enoyl-CoA. Catalytic activity: (S)-3-hydroxyacyl-CoA + NAD (+) = 3-oxoacyl-CoA + NADH. Disease: Absent in patients suffering with peroxisomal disorders such as Zellweger syndrome, neonatal adrenoleukodystrophy and infantile Refsum disease. pathway: Lipid metabolism; fatty acid beta-oxidation. similarity: In the C-terminal section; belongs to the 3-hydroxyacyl-CoA dehydrogenase family. similarity: In the N-terminal section; belongs to the enoyl-CoA hydratase/isomerase family. subunit: Monomer. tissue specificity: Liver and kidney. Lower amounts seen in the brain.

• UniProt :

  Q08426

• Swiss Prot :

  Q08426

• Reactivity :

  Human; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human EHHADH. AA range:476-525

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  80kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  80kD

• Fragment :

  IgG

• Subcellular Location :

  Peroxisome .

• Other Product Names :

  EHHADH; ECHD; Peroxisomal bifunctional enzyme; PBE; PBFE

• Gene ID (Human) :

  1962