Sarcoglycan-β rabbit pAb

• Background :

  This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy.[provided by RefSeq, Oct 2008]

• Description :

  This gene encodes a member of the sarcoglycan family. Sarcoglycans are transmembrane components in the dystrophin-glycoprotein complex which help stabilize the muscle fiber membranes and link the muscle cytoskeleton to the extracellular matrix. Mutations in this gene have been associated with limb-girdle muscular dystrophy. [provided by RefSeq, Oct 2008],

• UniProt :

  Q16585

• Swiss Prot :

  Q16585

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human Sarcoglycan-beta. AA range:87-136

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  43kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  43kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane, sarcolemma ; Single-pass type II membrane protein . Cytoplasm, cytoskeleton .

• Other Product Names :

  SGCB; Beta-sarcoglycan; Beta-SG; 43 kDa dystrophin-associated glycoprotein; 43DAG; A3b

• Gene ID (Human) :

  6443