SLK rabbit pAb

• Background :

  Catalytic activity:ATP + a protein = ADP + a phosphoprotein., function:Mediates apoptosis and actin stress fiber dissolution., PTM:Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Proteolytically cleaved by caspase-3., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 422., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 611., sequence caution:Contaminating sequence. Potential poly-A sequence starting in position 614., similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 UVR domain., tissue specificity:Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

• Description :

  Catalytic activity: ATP + a protein = ADP + a phosphoprotein. function: Mediates apoptosis and actin stress fiber dissolution. PTM: Autophosphorylated. Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Proteolytically cleaved by caspase-3. sequence Caution: Contaminating sequence. Potential poly-A sequence starting in position 422. sequence Caution: Contaminating sequence. Potential poly-A sequence starting in position 611. sequence Caution: Contaminating sequence. Potential poly-A sequence starting in position 614. similarity: Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. STE20 subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 1 UVR domain. tissue specificity: Ubiquitously expressed. Highest expression is found in heart and in skeletal muscle.

• Product Name Alternative :

  SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2

• UniProt :

  Q9H2G2

• Swiss Prot :

  Q9H2G2

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human SLK. AA range:1151-1200

• Target :

  SLK

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  150kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  150kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm .

• Other Product Names :

  SLK; KIAA0204; STK2; STE20-like serine/threonine-protein kinase; STE20-like kinase; hSLK; CTCL tumor antigen se20-9; STE20-related serine/threonine-protein kinase; STE20-related kinase; Serine/threonine-protein kinase 2

• Gene ID (Human) :

  9748