TAB182 rabbit pAb

• Background :

  PTM:ADP-ribosylated by TNKS1 (in vitro) ., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin., subunit:Binds to the ANK repeat domain of TNKS1 and TNKS2., tissue specificity:Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.

• Description :

  PTM: ADP-ribosylated by TNKS1 (in vitro). PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin. subunit: Binds to the ANK repeat domain of TNKS1 and TNKS2. tissue specificity: Detected in testis, ovary, lung, skeletal muscle, heart, prostate and pancreas, and at very low levels in brain and peripheral blood leukocytes.

• Product Name Alternative :

  TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein

• UniProt :

  Q9C0C2

• Swiss Prot :

  Q9C0C2

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human TNKS1BP1. AA range:1601-1650

• Target :

  TAB182

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  150kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  150kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus. Cytoplasm, cytoskeleton. Chromosome. Colocalizes with chromosomes during mitosis, and in the cytoplasm with cortical actin.

• Other Product Names :

  TNKS1BP1; KIAA1741; TAB182; 182 kDa tankyrase-1-binding protein

• Gene ID (Human) :

  85456