IL-31Rα rabbit pAb

• Background :

  The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR) . Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

• Description :

  The protein encoded by this gene belongs to the type I Cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011],

• Product Name Alternative :

  IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17

• UniProt :

  Q8NI17

• Swiss Prot :

  Q8NI17

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from the Internal region of human IL-31Rα.

• Target :

  IL-31Rα

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  82kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  82kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Single-pass type I membrane protein . Cell junction, synapse, presynaptic cell membrane . Cell projection, axon .

• Other Product Names :

  IL31RA; CRL3; GPL; Interleukin-31 receptor subunit alpha; IL-31 receptor subunit alpha; IL-31R subunit alpha; IL-31R-alpha; IL-31RA; Cytokine receptor-like 3; GLM-R; hGLM-R; Gp130-like monocyte receptor; Gp130-like receptor; ZcytoR17

• Gene ID (Human) :

  133396