RASSF8 rabbit pAb

• Background :

  This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t (12;22) (p11.2; q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011]

• Description :

  This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t (12;22) (p11. 2;q13. 3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2011],

• Product Name Alternative :

  RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

• UniProt :

  Q8NHQ8

• Swiss Prot :

  Q8NHQ8

• Reactivity :

  Human; Rat

• Immunogen :

  Synthesized peptide derived from RASSF8 . at AA range: 60-140

• Target :

  RASSF8

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  48kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  48kD

• Fragment :

  IgG

• Other Product Names :

  RASSF8; C12orf2; Ras association domain-containing protein 8; Carcinoma-associated protein HOJ-1

• Gene ID (Human) :

  11228