TREM-1 rabbit pAb

• Background :

  Triggering receptor expressed on myeloid cells 1 (TREM1) Homo sapiens This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

• Description :

  Triggering receptor expressed on myeloid cells 1 (TREM1) Homo sapiens This gene encodes a receptor belonging to the Ig superfamily that is expressed on myeloid cells. This protein amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene. [provided by RefSeq, Jun 2011],

• UniProt :

  Q9NP99

• Swiss Prot :

  Q9NP99

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from TREM-1 . at AA range: 40-120

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:100-500; IF/ICC 1:100-500; ELISA 1:5000-20000

• Molecular Weight :

  26kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  26kD

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Cell membrane ; Single-pass type I membrane protein . Recruited to lipid rafts when activated. .; [Isoform 2]: Secreted .

• Other Product Names :

  TREM1; Triggering receptor expressed on myeloid cells 1; TREM-1; Triggering receptor expressed on monocytes 1; CD354

• Gene ID (Human) :

  54210