Apelin rabbit pAb

• Background :

  This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016]

• Description :

  This gene encodes a peptide that functions as an endogenous ligand for the G-protein coupled apelin receptor. The encoded preproprotein is proteolytically processed into biologically active C-terminal peptide fragments. These peptide fragments activate different tissue specific signaling pathways that regulate diverse biological functions including fluid homeostasis, cardiovascular function and insulin secretion. This protein also functions as a coreceptor for the human immunodeficiency virus 1. [provided by RefSeq, Feb 2016],

• Product Name Alternative :

  APLN; APEL; Apelin; APJ endogenous ligand

• UniProt :

  Q9ULZ1

• Swiss Prot :

  Q9ULZ1

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the C-terminal region of human APLN. AA range:28-77

• Target :

  Apelin

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. IF 1:100-300 Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  16kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  16kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted . Secreted, extracellular space . Abundantly secreted in the colostrum. Lower level in milk. Decreases rapidly within several days after parturition in milk, but is still detectable even in commercial milk. .

• Other Product Names :

  APLN; APEL; Apelin; APJ endogenous ligand

• Gene ID (Human) :

  8862