MAPK Organizer 1 rabbit pAb

• Background :

  This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]

• Description :

  This gene encodes a member of the WD-40 protein family. The protein is proposed to function as a molecular scaffold for various multimeric protein complexes. The protein associates with several components of the extracellular signal-regulated kinase (ERK) pathway, and promotes ERK activity in response to serum or other signals. The protein also interacts with egl nine homolog 3 (EGLN3, also known as PHD3) and regulates expression of hypoxia-inducible factor 1, and has been purified as part of the spliceosome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009],

• Product Name Alternative :

  WDR83; MORG1; WD repeat domain-containing protein 83; Mitogen-activated protein kinase organizer 1; MAPK organizer 1

• UniProt :

  Q9BRX9

• Swiss Prot :

  Q9BRX9

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human WDR83. AA range:141-190

• Target :

  MAPK Organizer 1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1/100-1/300. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  34kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  34kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus . Predominantly cytoplasmic. Partially nuclear. .

• Other Product Names :

  WDR83; MORG1; WD repeat domain-containing protein 83; Mitogen-activated protein kinase organizer 1; MAPK organizer 1

• Gene ID (Human) :

  84292