Dkk-1 rabbit pAb

• Background :

  This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes a protein that is a member of the dickkopf family. It is a secreted protein with two cysteine rich regions and is involved in embryonic development through its inhibition of the WNT signaling pathway. Elevated levels of DKK1 in bone marrow plasma and peripheral blood is associated with the presence of osteolytic bone lesions in patients with multiple myeloma. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK

• UniProt :

  O94907

• Swiss Prot :

  O94907

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the C-terminal region of human DKK1. AA range:181-230

• Target :

  Dkk-1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  29kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  29kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted.

• Other Product Names :

  DKK1; Dickkopf-related protein 1; Dickkopf-1; Dkk-1; hDkk-1; SK

• Gene ID (Human) :

  22943