Epac rabbit pAb

• Background :

  Caution:It is uncertain whether Met-1 or Met-43 is the initiator., domain:The DEP domain is involved in membrane localization independent from regulation by cAMP., function:Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP., similarity:Contains 1 cyclic nucleotide-binding domain., similarity:Contains 1 DEP domain., similarity:Contains 1 N-terminal Ras-GEF domain., similarity:Contains 1 Ras-GEF domain., tissue specificity:Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.

• Description :

  Caution: It is uncertain whether Met-1 or Met-43 is the initiator. Domain: The DEP domain is involved in membrane localization independent from regulation by cAMP. function: Guanine nucleotide exchange factor (GEF) for RAP1A and RAP2A small GTPases that is activated by binding cAMP. similarity: Contains 1 cyclic nucleotide-binding domain. similarity: Contains 1 DEP domain. similarity: Contains 1 N-terminal Ras-GEF domain. similarity: Contains 1 Ras-GEF domain. tissue specificity: Widely expressed with highest levels in adult kidney, heart, thyroid and brain, and fetal kidney.

• Product Name Alternative :

  RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

• UniProt :

  O95398

• Swiss Prot :

  O95398

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RAPGEF3. AA range:712-761

• Target :

  Epac

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  100kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  100kD

• Fragment :

  IgG

• Subcellular Location :

  Endomembrane system .

• Other Product Names :

  RAPGEF3; CGEF1; EPAC; EPAC1; Rap guanine nucleotide exchange factor 3; Exchange factor directly activated by cAMP 1; Exchange protein directly activated by cAMP 1; EPAC 1; Rap1 guanine-nucleotide-exchange factor directly activated by cAMP

• Gene ID (Human) :

  10411