NHE-6 rabbit pAb

• Background :

  This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants.[provided by RefSeq, Apr 2010]

• Description :

  This gene encodes a sodium-hydrogen exchanger that is amember of the solute carrier family 9. The encoded protein localizes to early and recycling endosomes and may be involved in regulating endosomal pH and volume. Defects in this gene are associated with X-linked syndromic mental retardation, Christianson type. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2010],

• Product Name Alternative :

  SLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na (+) /H (+) exchanger 6; NHE-6; Solute carrier family 9 member 6

• UniProt :

  Q92581

• Swiss Prot :

  Q92581

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human SLC9A6. AA range:551-600

• Target :

  NHE-6

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  75kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  75kD

• Fragment :

  IgG

• Subcellular Location :

  Endosome membrane ; Multi-pass membrane protein . Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.; [Isoform 2]: Recycling endosome membrane ; Multi-pass membrane protein .

• Other Product Names :

  SLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na (+) /H (+) exchanger 6; NHE-6; Solute carrier family 9 member 6

• Gene ID (Human) :

  10479