Ataxin-2L rabbit pAb

• Background :

  This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Description :

  This gene encodes an ataxin type 2 related protein of unknown function. This protein is a member of the spinocerebellar ataxia (SCAs) family, which is associated with a complex group of neurodegenerative disorders. Several alternatively spliced transcripts encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  ATXN2L; A2D; A2LG; A2LP; A2RP; Ataxin-2-like protein; Ataxin-2 domain protein; Ataxin-2-related protein

• UniProt :

  Q8WWM7

• Swiss Prot :

  Q8WWM7

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ATXN2L. AA range:571-620

• Target :

  Ataxin-2L

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  113kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  113kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane ; Peripheral membrane protein . Cytoplasm . Nucleus speckle . Cytoplasmic granule . Predominantly cytoplasmic but is also detected in nuclear speckles (PubMed:23209657) . Component of cytoplasmic stress granules (PubMed:23209657) . Inhibition of methylation alters nuclear localization (PubMed:25748791) . Methylation does not seem to be required for localization to stress granules under stress conditions (PubMed:25748791) . .

• Other Product Names :

  ATXN2L; A2D; A2LG; A2LP; A2RP; Ataxin-2-like protein; Ataxin-2 domain protein; Ataxin-2-related protein

• Gene ID (Human) :

  11273