TPH2 (phospho Ser19) rabbit pAb

• Background :

  This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016]

• Description :

  This gene encodes a member of the pterin-dependent aromatic acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene may be associated with psychiatric diseases such as bipolar affective disorder and major depression. [provided by RefSeq, Feb 2016],

• Product Name Alternative :

  TPH2; NTPH; Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2

• UniProt :

  Q8IWU9

• Swiss Prot :

  Q8IWU9

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized phospho-peptide around the phosphorylation site of human TPH2 (phospho Ser19)

• Target :

  TPH2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  56kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  56kD

• Fragment :

  IgG

• Subcellular Location :

  Cytosol, neuron projection

• Other Product Names :

  TPH2; NTPH; Tryptophan 5-hydroxylase 2; Neuronal tryptophan hydroxylase; Tryptophan 5-monooxygenase 2

• Gene ID (Human) :

  121278