Repetin rabbit pAb

• Background :

  Domain:Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats., function:Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., PTM:Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase., similarity:Belongs to the S100-fused protein family., similarity:Contains 2 EF-hand domains., tissue specificity:Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.

• Description :

  Domain: Can be divided into a N-terminal domain with significant homology to S100-like calcium-binding proteins, a central domain containing a series of short tandem repeats, and two flanking segments with low homology to the consensus sequences of the central repeats. function: Involved in the cornified cell envelope formation. Multifunctional epidermal matrix protein. Reversibly binds calcium. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. PTM: Potential substrate of transglutaminase. Some arginines are probably converted to citrullines by peptidylarginine deimidase. similarity: Belongs to the S100-fused protein family. similarity: Contains 2 EF-hand domains. tissue specificity: Expression is scattered in the normal epidermis but strong in the acrosyringium, the inner hair root sheat and in the filiform papilli of the tongue.

• Product Name Alternative :

  RPTN; Repetin

• UniProt :

  Q6XPR3

• Swiss Prot :

  Q6XPR3

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RPTN. AA range:648-697

• Target :

  Repetin

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  90kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  90kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted, extracellular space, extracellular matrix.

• Other Product Names :

  RPTN; Repetin

• Gene ID (Human) :

  126638