TPX2 rabbit pAb

• Background :

  Developmental stage:Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis., PTM:Phosphorylated upon DNA damage, probably by ATM or ATR., subcellular location:During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus., tissue specificity:Expressed in lung carcinoma cell lines but not in normal lung tissues.

• Description :

  Developmental stage: Exclusively expressed in proliferating cells from the transition G1/S until the end of cytokinesis. PTM: Phosphorylated upon DNA damage, probably by ATM or ATR. subcellular location: During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. tissue specificity: Expressed in lung carcinoma cell lines but not in normal lung tissues.

• Product Name Alternative :

  TPX2; C20orf1; C20orf2; DIL2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein fls353; Restricted expression prolifera

• UniProt :

  Q9ULW0

• Swiss Prot :

  Q9ULW0

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human DIL-2. AA range:301-350

• Target :

  TPX2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  86kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  86kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Cytoplasm, cytoskeleton, spindle . Cytoplasm, cytoskeleton, spindle pole . During mitosis it is strictly associated with the spindle pole and with the mitotic spindle, whereas during S and G2, it is diffusely distributed throughout the nucleus. Is released from the nucleus in apoptotic cells and is detected on apoptotic microtubules. .

• Other Product Names :

  TPX2; C20orf1; C20orf2; DIL2; HCA519; Targeting protein for Xklp2; Differentially expressed in cancerous and non-cancerous lung cells 2; DIL-2; Hepatocellular carcinoma-associated antigen 519; Protein fls353; Restricted expression prolifera

• Gene ID (Human) :

  22974