Raftlin rabbit pAb

• Background :

  Function:May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling., similarity:Belongs to the raftlin family., subcellular location:Associates with lipid rafts., tissue specificity:Specifically expressed by B-cells (at protein level) .

• Description :

  Function: May play a pivotal role in the formation and/or maintenance of lipid rafts. May regulate B-cell antigen receptor-mediated signaling. similarity: Belongs to the raftlin family. subcellular location: Associates with lipid rafts. tissue specificity: Specifically expressed by B-cells (at protein level).

• Product Name Alternative :

  RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein

• UniProt :

  Q14699

• Swiss Prot :

  Q14699

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RFTN1. AA range:432-481

• Target :

  Raftlin

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  65kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  65kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Lipid-anchor . Cytoplasm . Membrane raft . Endosome . Early endosome . Translocates from cytoplasm to cell membrane where it colocalizes with poly (I:C) and then moves to endosomes where it colocalizes with TLR3 (PubMed:21266579) . Translocates from cytoplasm to cell membrane where it colocalizes with TLR4 and then together with TLR4 moves to endosomes, upon lipopolysaccharide stimulation (PubMed:27022195) . .

• Other Product Names :

  RFTN1; KIAA0084; MIG2; Raftlin; Cell migration-inducing gene 2 protein; Raft-linking protein

• Gene ID (Human) :

  23180