Tensin-2 (phospho Tyr483) rabbit pAb

• Background :

  The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008]

• Description :

  The protein encoded by this gene belongs to the tensin family. Tensin is a focal adhesion molecule that binds to actin filaments and participates in signaling pathways. This protein plays a role in regulating cell migration. Alternative splicing occurs at this locus and three transcript variants encoding three distinct isoforms have been identified. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

• UniProt :

  Q63HR2

• Swiss Prot :

  Q63HR2

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized phospho-peptide around the phosphorylation site of human Tensin-2 (phospho Tyr483)

• Target :

  Tensin-2

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  152kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  152kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, focal adhesion . Cell membrane ; Peripheral membrane protein ; Cytoplasmic side . Detected at the end of actin stress fibers. Detected in cytoplasmic punctate bodies (PubMed:22019427) . .

• Other Product Names :

  TENC1; KIAA1075; TNS2; Tensin-like C1 domain-containing phosphatase; C1 domain-containing phosphatase and tensin homolog; C1-TEN; Tensin-2

• Gene ID (Human) :

  23371