MRGX1 rabbit pAb

• Background :

  Function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) . BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha) q proteins are involved in the calcium-signaling pathway., similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily., tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

• Description :

  Function: Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha)q proteins are involved in the calcium-signaling pathway. similarity: Belongs to the G-protein coupled receptor 1 family. Mas subfamily. tissue specificity: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.

• Product Name Alternative :

  MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4

• UniProt :

  Q96LB2

• Swiss Prot :

  Q96LB2

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human MRGX1. AA range:271-320

• Target :

  MRGX1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000; IHC-p 1:50-300

• Buffer :

  -20°C/1 year

• Molecular Weight :

  36kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  36kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane; Multi-pass membrane protein.

• Other Product Names :

  MRGPRX1; MRGX1; SNSR3; SNSR4; Mas-related G-protein coupled receptor member X1; Sensory neuron-specific G-protein coupled receptor 3/4

• Gene ID (Human) :

  259249