P52 S6 kinase rabbit pAb

• Background :

  Catalytic activity:ATP + a protein = ADP + a phosphoprotein., caution:Instead of Lys-820, Arg-820 is found at the binding site., domain:The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site., function:May be involved in transmitting sphingosine-1 phosphate (SPP) -mediated signaling into the cell., similarity:Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily., similarity:Contains 1 MIT domain., similarity:Contains 1 PX (phox homology) domain., similarity:Contains 2 protein kinase domains., subcellular location:Also found in some small dot-like or ring-shaped early endosome structures., subunit:Interacts with SPHK1 and phosphatidylinositol 3-phosphate., tissue specificity:Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.

• Description :

  Catalytic activity: ATP + a protein = ADP + a phosphoprotein. Caution: Instead of Lys-820, Arg-820 is found at the binding site. Domain: The first protein kinase domain appears to be a pseudokinase domain as it does not contain the classical characteristics, such as the ATP-binding motif, ATP-binding site and active site. function: May be involved in transmitting sphingosine-1 phosphate (SPP)-mediated signaling into the cell. similarity: Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. S6 kinase subfamily. similarity: Contains 1 MIT domain. similarity: Contains 1 PX (phox homology) domain. similarity: Contains 2 protein kinase domains. subcellular location: Also found in some small dot-like or ring-shaped early endosome structures. subunit: Interacts with SPHK1 and phosphatidylinositol 3-phosphate. tissue specificity: Highly expressed in testis, skeletal muscle, brain, heart, placenta, kidney and liver and weakly expressed in thymus, small intestine, lung and colon.

• Product Name Alternative :

  RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein

• UniProt :

  Q96S38

• Swiss Prot :

  Q96S38

• Reactivity :

  Human; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human RPS6KC1. AA range:231-280

• Target :

  P52 S6 kinase

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  117kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  117kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Membrane . Early endosome .

• Other Product Names :

  RPS6KC1; RPK118; Ribosomal protein S6 kinase delta-1; S6K-delta-1; 52 kDa ribosomal protein S6 kinase; Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein; SPHK1-binding protein

• Gene ID (Human) :

  26750