HBP1 (phospho Ser402) rabbit pAb

• Background :

  Function:Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4., similarity:Contains 1 AXH domain., similarity:Contains 1 HMG box DNA-binding domain., subunit:Binds the second PAH repeat of SIN3A (By similarity) . Binds TCF4 and RB1.

• Description :

  Function: Transcriptional repressor that binds to the promoter region of target genes. Plays a role in the regulation of the cell cycle and of the Wnt pathway. Binds preferentially to the sequence 5'-TTCATTCATTCA-3'. Binding to the H1F0 promoter is enhanced by interaction with RB1. Disrupts the interaction between DNA and TCF4. similarity: Contains 1 AXH domain. similarity: Contains 1 HMG box DNA-binding domain. subunit: Binds the second PAH repeat of SIN3A (By similarity). Binds TCF4 and RB1.

• Product Name Alternative :

  HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1

• UniProt :

  O60381

• Swiss Prot :

  O60381

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human HBP1 around the phosphorylation site of Ser402. AA range:371-420

• Target :

  HBP1

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  58kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  58kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  HBP1; HMG box-containing protein 1; HMG box transcription factor 1; High mobility group box transcription factor 1

• Gene ID (Human) :

  26959