Arylsulfatase A rabbit pAb

• Background :

  The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]

• Description :

  The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010],

• UniProt :

  P15289

• Swiss Prot :

  P15289

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ARSA. AA range:251-300

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  54kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  54kD

• Fragment :

  IgG

• Subcellular Location :

  Endoplasmic reticulum . Lysosome .

• Other Product Names :

  ARSA; Arylsulfatase A; ASA; Cerebroside-sulfatase

• Gene ID (Human) :

  410