TEM7 rabbit pAb

• Background :

  PTM:N-glycosylated., similarity:Belongs to the plexin family., subunit:May interact with cortactin., tissue specificity:Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue.

• Description :

  PTM: N-glycosylated. similarity: Belongs to the plexin family. subunit: May interact with cortactin. tissue specificity: Detected in endothelial cells from colorectal cancer, and in endothelial cells from primary cancers of the lung, liver, pancreas, breast and brain. Not detectable in endothelial cells from normal tissue.

• UniProt :

  Q8IUK5

• Swiss Prot :

  Q8IUK5

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human PLXDC1. AA range:71-120

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  [Isoform 1]: Cell membrane; Single-pass type I membrane protein. Cell junction, tight junction. Localized predominantly at the tight junctions of vascular endothelial cells and to a lesser extent at the luminal surface of vascular endothelial cells.; [Isoform 2]: Secreted .; [Isoform 3]: Secreted .; [Isoform 4]: Cytoplasm .

• Other Product Names :

  PLXDC1; TEM3; TEM7; Plexin domain-containing protein 1; Tumor endothelial marker 3; Tumor endothelial marker 7

• Gene ID (Human) :

  57125