ETL rabbit pAb

• Background :

  Developmental stage:Up-regulated in the adult heart., domain:The transmembrane domain is not required for cleavage, but it is required for dimer formation., function:Could be involved in cardiac development., PTM:Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit., similarity:Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily., similarity:Contains 1 GPS domain., similarity:Contains 2 EGF-like domains., subunit:Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit) . Forms stable dimer at the cells surface., tissue specificity:Mainly expressed in smooth muscle.

• Description :

  Developmental stage: Up-regulated in the adult heart. Domain: The transmembrane domain is not required for cleavage, but it is required for dimer formation. function: Could be involved in cardiac development. PTM: Proteolytically cleaved into 2 subunits, an extracellular alpha subunit and a seven-transmembrane subunit. similarity: Belongs to the G-protein coupled receptor 2 family. LN-TM7 subfamily. similarity: Contains 1 GPS domain. similarity: Contains 2 EGF-like domains. subunit: Forms a heterodimer, consisting of a large extracellular region (alpha subunit) non-covalently linked to a seven-transmembrane moiety (beta subunit). Forms stable dimer at the cells surface. tissue specificity: Mainly expressed in smooth muscle.

• UniProt :

  Q9HBW9

• Swiss Prot :

  Q9HBW9

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ELTD1. AA range:251-300

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.

• Molecular Weight :

  77kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  77kD

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Multi-pass membrane protein .

• Other Product Names :

  ELTD1; ETL; EGF; latrophilin and seven transmembrane domain-containing protein 1; EGF-TM7-latrophilin-related protein; ETL protein

• Gene ID (Human) :

  64123