Txk rabbit pAb

• Background :

  Catalytic activity:ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate., similarity:Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily., similarity:Contains 1 protein kinase domain., similarity:Contains 1 SH2 domain., similarity:Contains 1 SH3 domain., tissue specificity:Expressed in T-cells and some myeloid cell lines.

• Description :

  Catalytic activity: ATP + a [protein]-L-tyrosine = ADP + a [protein]-L-tyrosine phosphate. similarity: Belongs to the protein kinase superfamily. Tyr protein kinase family. TEC subfamily. similarity: Contains 1 protein kinase domain. similarity: Contains 1 SH2 domain. similarity: Contains 1 SH3 domain. tissue specificity: Expressed in T-cells and some myeloid cell lines.

• UniProt :

  P42681

• Swiss Prot :

  P42681

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from the Internal region of human Txk.

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Nucleus . Cell membrane ; Peripheral membrane protein . Localizes in the vicinity of cell surface receptors in the plasma membrane after receptor stimulation. Translocates into the nucleus and enhances IFN-gamma gene transcription in T-cells.

• Other Product Names :

  TXK; PTK4; RLK; Tyrosine-protein kinase TXK; Protein-tyrosine kinase 4; Resting lymphocyte kinase

• Gene ID (Human) :

  7294