14-3-3 η rabbit pAb

• Background :

  This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009]

• Description :

  This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to the mouse, rat and bovine orthologs. This gene contains a 7 bp repeat sequence in its 5' UTR, and changes in the number of this repeat have been associated with early-onset schizophrenia and psychotic bipolar disorder. [provided by RefSeq, Jun 2009],

• Product Name Alternative :

  YWHAH; YWHA1; 14-3-3 protein eta; Protein AS1

• UniProt :

  Q04917

• Swiss Prot :

  Q04917

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human 14-3-3 eta. AA range:51-100

• Target :

  14-3-3 η

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  42kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  42kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, mitochondrion, cytosol, plasma membrane, intercalated disc, cytoplasmic vesicle membrane, extracellular exosome

• Other Product Names :

  YWHAH; YWHA1; 14-3-3 protein eta; Protein AS1

• Gene ID (Human) :

  7533