Rab11-FIP1 rabbit pAb

• Background :

  This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]

• Description :

  This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013],

• UniProt :

  Q6WKZ4

• Swiss Prot :

  Q6WKZ4

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from Rab11-FIP1 . at AA range: 70-150

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Recycling endosome . Rab11A rather than Rab4A mediates localization in the endocytic recycling compartment (ERC) .; [Isoform 2]: Cytoplasmic vesicle, phagosome membrane. Membrane-bound (isoform 2) . Colocalizes with Rab11A at phagosomes (isoform 2) .

• Other Product Names :

  RAB11FIP1; RCP; Rab11 family-interacting protein 1; Rab11-FIP1; Rab-coupling protein

• Gene ID (Human) :

  80223