Frizzled-4 rabbit pAb

• Background :

  Frizzled class receptor 4 (FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008]

• Description :

  Frizzled class receptor 4 (FZD4) Homo sapiens This gene is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. This protein may play a role as a positive regulator of the Wingless type MMTV integration site signaling pathway. A transcript variant retaining intronic sequence and encoding a shorter isoform has been described, however, its expression is not supported by other experimental evidence. [provided by RefSeq, Jul 2008],

• Product Name Alternative :

  FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

• UniProt :

  Q9ULV1

• Swiss Prot :

  Q9ULV1

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human FZD4. AA range:131-180

• Target :

  Frizzled-4

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunofluorescence: 1/200 - 1/1000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Storage Conditions :

  -20°C/1 year

• Fragment :

  IgG

• Subcellular Location :

  Cell membrane ; Multi-pass membrane protein .

• Other Product Names :

  FZD4; Frizzled-4; Fz-4; hFz4; FzE4; CD antigen CD344

• Gene ID (Human) :

  8322