BCL2L12 rabbit pAb

• Background :

  This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2) . The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

• Description :

  This gene encodes a member of a family of proteins containing a Bcl-2 homology domain 2 (BH2). The encoded protein is an anti-apoptotic factor that acts as an inhibitor of caspases 3 and 7 in the cytoplasm. In the nucleus, it binds to the p53 tumor suppressor protein, preventing its association with target genes. Overexpression of this gene has been detected in a number of different cancers. There is a pseudogene for this gene on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013],

• Product Name Alternative :

  BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

• UniProt :

  Q9HB09

• Swiss Prot :

  Q9HB09

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from BCL2L12 . at AA range: 60-140

• Target :

  BCL2L12

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  34kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  34kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus, membrane

• Other Product Names :

  BCL2L12; BPR; Bcl-2-like protein 12; Bcl2-L-12; Bcl-2-related proline-rich protein

• Gene ID (Human) :

  83596