P130 Cas (phospho Tyr410) rabbit pAb

• Background :

  BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al., 2006 [PubMed 17129785]) .[supplied by OMIM, May 2009]

• Description :

  BCAR1, or CAS, is an Src (MIM 190090) family kinase substrate involved in various cellular events, including migration, survival, transformation, and invasion (Sawada et al. 2006 [PubMed 17129785]). [supplied by OMIM, May 2009],

• UniProt :

  P56945

• Swiss Prot :

  P56945

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human p130 Cas around the phosphorylation site of Tyr410. AA range:376-425

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.

• Molecular Weight :

  130kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  130kD

• Fragment :

  IgG

• Subcellular Location :

  Cell junction, focal adhesion . Cytoplasm . Cell projection, axon . Unphosphorylated form localizes in the cytoplasm (By similarity) . Localizes to focal adhesion sites following integrin engagement (By similarity) . .

• Other Product Names :

  BCAR1; CAS; CASS1; CRKAS; Breast cancer anti-estrogen resistance protein 1; CRK-associated substrate; Cas scaffolding protein family member 1; p130cas

• Gene ID (Human) :

  9564