CEP41 rabbit pAb

• Background :

  This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012]

• Description :

  This gene encodes a centrosomal and microtubule-binding protein which is predicted to have two coiled-coil domains and a rhodanese domain. In human retinal pigment epithelial cells the protein localized to centrioles and cilia. Mutations in this gene have been associated with Joubert Syndrome 15; an autosomal recessive ciliopathy and neurological disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2012],

• UniProt :

  Q9BYV8

• Swiss Prot :

  Q9BYV8

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human CEP41. AA range:150-200

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.

• Molecular Weight :

  41kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  41kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell projection, cilium. Cytoplasm, cytoskeleton, cilium basal body. Localizes mainly to the cilium basal body and in primary cilia.

• Other Product Names :

  CEP41; TSGA14; Centrosomal protein of 41 kDa; Cep41; Testis-specific gene A14 protein

• Gene ID (Human) :

  95681