ARHGAP11A rabbit pAb

• Background :

  This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016]

• Description :

  This gene encodes a member of the Rho GTPase activating protein family. In response to DNA damage, the encoded protein interacts with the p53 tumor suppressor protein and stimulates its tetramerization, which results in cell-cycle arrest and apoptosis. A chromosomal deletion that includes this gene is one cause of Prader-Willi syndrome, and an intronic variant of this gene may be associated with sleep duration in children. This gene is highly expressed in colon cancers and in a human basal-like breast cancer cell line. [provided by RefSeq, Sep 2016],

• Product Name Alternative :

  ARHGAP11A; KIAA0013; Rho GTPase-activating protein 11A; Rho-type GTPase-activating protein 11A

• UniProt :

  Q6P4F7

• Swiss Prot :

  Q6P4F7

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from human ARHGAP11A. AA range:471-520

• Target :

  ARHGAP11A

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/40000. Not yet tested in other applications.

• Buffer :

  -20°C/1 year

• Molecular Weight :

  110kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  110kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus .

• Other Product Names :

  ARHGAP11A; KIAA0013; Rho GTPase-activating protein 11A; Rho-type GTPase-activating protein 11A

• Gene ID (Human) :

  9824