Calretinin rabbit pAb

• Background :

  This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010]

• Description :

  This gene encodes an intracellular calcium-binding protein belonging to the troponin C superfamily. Members of this protein family have six EF-hand domains which bind calcium. This protein plays a role in diverse cellular functions, including message targeting and intracellular calcium buffering. It also functions as a modulator of neuronal excitability, and is a diagnostic marker for some human diseases, including Hirschsprung disease and some cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2010],

• UniProt :

  P22676

• Swiss Prot :

  P22676

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized peptide derived from calbindin 2 at AA range: 191-240

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.

• Molecular Weight :

  32kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  32kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus, cytoplasm, cytosol, gap junction, neuron projection, terminal bouton, synapse

• Other Product Names :

  Calretinin (CR;29 kDa calbindin)

• Gene ID (Human) :

  794