Acetyl-EPAS-1 (K385) rabbit pAb

• Background :

  Endothelial PAS domain protein 1 (EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009]

• Description :

  Endothelial PAS domain protein 1 (EPAS1) Homo sapiens This gene encodes a transcription factor involved in the induction of genes regulated by oxygen, which is induced as oxygen levels fall. The encoded protein contains a basic-helix-loop-helix domain protein dimerization domain as well as a domain found in proteins in signal transduction pathways which respond to oxygen levels. Mutations in this gene are associated with erythrocytosis familial type 4. [provided by RefSeq, Nov 2009],

• UniProt :

  Q99814

• Swiss Prot :

  Q99814

• Reactivity :

  Human; Mouse; Rat

• Immunogen :

  Synthesized acetyl-peptide of Acetyl-EPAS-1 (K385)

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, ELISA 1:10000-20000

• Molecular Weight :

  120kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  120kD

• Fragment :

  IgG

• Subcellular Location :

  Nucleus . Nucleus speckle . Colocalizes with HIF3A in the nucleus and speckles. .

• Other Product Names :

  Endothelial PAS domain protein 1

• Gene ID (Human) :

  2034