IL-31 rabbit pAb

• Background :

  IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al., 2004 [PubMed 15184896]) .[supplied by OMIM, Mar 2008]

• Description :

  IL31, which is made principally by activated Th2-type T cells, interacts with a heterodimeric receptor consisting of IL31RA (MIM 609510) and OSMR (MIM 601743) that is constitutively expressed on epithelial cells and keratinocytes. IL31 may be involved in the promotion of allergic skin disorders and in regulating other allergic diseases, such as asthma (Dillon et al. 2004 [PubMed 15184896]). [supplied by OMIM, Mar 2008],

• Product Name Alternative :

  Interleukin-31 (IL-31)

• UniProt :

  Q6EBC2

• Swiss Prot :

  Q6EBC2

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  The antiserum was produced against synthesized peptide derived from the Internal region of human IL31. AA range:21-70

• Target :

  IL-31

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; IHC; IF; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000, IHC-p 1:50-200 ELISA 1:10000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  65kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  65kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted .

• Other Product Names :

  Interleukin-31 (IL-31)

• Gene ID (Human) :

  386653