ATS13 rabbit pAb

• Background :

  This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF) . Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

• Description :

  This gene encodes a member of a family of proteins containing several distinct regions, including a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. The enzyme encoded by this gene specifically cleaves von Willebrand Factor (vWF). Defects in this gene are associated with thrombotic thrombocytopenic purpura. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013],

• UniProt :

  Q76LX8

• Swiss Prot :

  Q76LX8

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 940-1020

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  156kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  156kD

• Fragment :

  IgG

• Subcellular Location :

  Secreted . Secretion enhanced by O-fucosylation of TSP type-1 repeats.

• Gene ID (Human) :

  11093