PREX1 rabbit pAb

• Background :

  Phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 (PREX1) Homo sapiens The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs) . It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]

• Description :

  Phosphatidylinositol-3, 4, 5-trisphosphate dependent Rac exchange factor 1 (PREX1) Homo sapiens The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3, 4, 5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008],

• UniProt :

  Q8TCU6

• Swiss Prot :

  Q8TCU6

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 340-420

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  182kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  182kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm, cytosol. Cell membrane. Mainly cytosolic. Some amount is apparently associated to the plasma membrane.

• Gene ID (Human) :

  57580