GRIP2 rabbit pAb

• Background :

  Domain:PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4., function:May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons., similarity:Belongs to the GRIP2 family., similarity:Contains 7 PDZ (DHR) domains., subunit:Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity) . Interacts with the C-terminal tail of PRLHR.

• Description :

  Domain: PDZ 5 mediates the C-terminal binding of GRIA2 and GRIA3. PDZ 6 mediates interaction with the PDZ recognition motif of EFNB1. PDZ 7 mediates interaction with CSPG4. function: May play a role as a localized scaffold for the assembly of a multiprotein signaling complex and as mediator of the trafficking of its binding partners at specific subcellular location in neurons. similarity: Belongs to the GRIP2 family. similarity: Contains 7 PDZ (DHR) domains. subunit: Interacts with EFNB1, EFNB3, GRIA2, GRIA3, CSPG4 and GRIPAP1. Can form homomultimers and heteromultimers with GRIP1 (By similarity). Interacts with the C-terminal tail of PRLHR.

• UniProt :

  Q9C0E4

• Swiss Prot :

  Q9C0E4

• Reactivity :

  Human; Rat; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 780-860

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Molecular Weight :

  114kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  114kD

• Fragment :

  IgG

• Subcellular Location :

  Cytoplasm . Membrane ; Peripheral membrane protein .

• Gene ID (Human) :

  80852