NPY6R rabbit pAb

• Background :

  Caution:Could be the product of a pseudogene. According to PubMed:97066888, PubMed:97066971 and PubMed:9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain., function:When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function., similarity:Belongs to the G-protein coupled receptor 1 family., tissue specificity:Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.

• Description :

  Caution: Could be the product of a pseudogene. According to PubMed: 97066888, PubMed: 97066971 and PubMed: 9013614, the human NPY6R gene is an expressed pseudogene containing a premature stop codon and encoding a non-functional truncated protein missing the last transmembrane domain. A single base pair deletion relative to the mouse ortholog, results in a truncated protein lacking the seventh transmembrane domain. function: When expressed, is unable to bind pancreatic polypeptide (PP), neuropeptide Y (NPY), or peptide YY (PYY), suggesting that either it is functionally inactive or that it may have acquired a pancreatic polypeptide-independent function. similarity: Belongs to the G-protein coupled receptor 1 family. tissue specificity: Expressed in heart, skeletal muscle, gastrointestinal tissues, spleen, brain and adrenal glands.

• UniProt :

  Q99463

• Swiss Prot :

  Q99463

• Reactivity :

  Human; Mouse

• Immunogen :

  Synthesized peptide derived from human protein . at AA range: 190-270

• Target :

  NPY6R

• Clonality :

  Polyclonal

• Source :

  Rabbit

• Applications :

  WB; ELISA

• Concentration :

  1 mg/ml

• Dilution :

  WB 1:500-2000 ELISA 1:5000-20000

• Buffer :

  -20°C/1 year

• Molecular Weight :

  31kD

• Storage Conditions :

  -20°C/1 year

• Observed Molecular Weight :

  31kD

• Fragment :

  IgG

• Subcellular Location :

  Membrane ; Multi-pass membrane protein .